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Acrodermatitis enteropathica is an autosomal recessive metabolic disorder affecting the uptake of zinc, characterized by periorificial (around the natural orifices) and acral (in the limbs) dermatitis, alopecia (loss of hair), and diarrhea. Similar features may be present in acquired zinc deficiency. This disease also is related to deficiency of zinc due to congenital causes. Other names for ''acrodermatitis enteropathica'' include: * Brandt syndrome * Danbolt–Closs syndrome〔Stedman, Thomas Lathrop. 2005. ''Stedman's Medical Eponyms.'' Baltimore: Lippincott Williams & Wilkins, p. 170.〕 * Congenital zinc deficiency ==Signs and symptoms== Features of acrodermatitis enteropathica start appearing in the first few months of life, as the infant discontinues breast milk. There are erythematous patches and plaques of dry, scaly skin. The lesions may appear eczematous, or may evolve further into crusted vesicles, bullas or pustules. The lesions are frequent around the mouth and anus, and also in hands, feet and, scalp. There may be suppurative inflammation of the nail fold surrounding the nail plate, known as paronychia. Alopecia (loss of hair from the scalp, eyebrows, and eyelashes) may occur. The skin lesions may be secondarily infected by bacteria such as Staphylococcus aureus or fungi like Candida albicans. These skin lesions are accompanied by diarrhea. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「acrodermatitis enteropathica」の詳細全文を読む スポンサード リンク
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